Jian Liu

Professor

B. Sc.in Materials Chemistry, Fudan University(China), 1997

M. Sc. in Macromolecular Chemistry and Physics, Fudan University(China), 2000

Ph.D.in Chemistry, Caltech (US), 2007

Postdoctoral research, Emory University, 2007-2009

Professor, FUNSOM Institute of Soochow University, since 2011

TEL: 0512-65884565

Email: jliu@suda.edu.cn

Research interests:

BioMEMS and Microfluidic Devices

Nano Probes for Bioanalytical Chemistry

Biomaterials for Tissue Engineering

Main contributions and projects:

Prof. Jian Liu’s research group (iMINTS Lab) focuses on developing functional nano materials and highly integrated microfluidic platforms for biomedical applications. These include new tools to detect biomarkers for early diagnosis of diseases, development of personalized therapies, and demand-based designs of biomaterials for regenerative medicine. Advances in these fields are highly translational, promising tremendous benefits for human health. Our team is very interested in exploring the new understanding on the properties of nano materials by synchrotron radiation-based techniques.

Group Webpage: http://web.suda.edu.cn/jliu/index.html 

Selected publications:

1. Hybrid CuCoO-GO Enables Ultrasensitive Detection of Antibiotics with Enhanced Laser Desorption/Ionization at Nano-interfaces.  Enhui Wu, Kun Feng, Rui Shi, Rui Lv, Fuzhong Ouyang, Shawn Li, Jun Zhong* and Jian Liu*. Chemical Science, 2019, 10, 257–267

2. Sensitive Detection of Single-cell Secreted H2O2 by Integrating a Microfluidic Droplet Sensor and Au Nanoclusters. Rui Shen, Peipei Liu, Yiqiu Zhang, Zhao Yu, Xuyue Chen, Lu Zhou, Baoqing Nie, Anna Zaczek, Jian Chen*, Jian Liu*. Analytical Chemistry, 2018, 90, 7, 4478-4484

3. Hydroxyl-Group-Dominated Graphite Dots Reshape Laser Desorption/Ionization Mass Spectrometry for Small Biomolecular Analysis and Imaging.  Rui Shi, Xing Dai, Weifeng Li, Fang Lu, Yang Liu, Huihua Qu, Hao Li, Qiongyang Chen, He Tian, Enhui Wu, Yong Wang, Ruhong Zhou*, Shuit-Tong Lee*, Yeshayahu Lifshitz, Zhenhui Kang*, and Jian Liu*. ACS Nano, 2017, 11, 9500-9513

4. Mitophagy Induced by Nanoparticle-Peptide Conjugates Enabling An Alternative Intracellular Trafficking Route. Zhaolei Zhang, Lei Zhou, Yanqing Zhou, Jinyin Liu, Xiaoyun Xing, Jun Zhong, Guoqiang Xu, Zhenhui Kang., Jian Liu*. Biomaterials, 2015, 65, 56-65.

5. Molecular mapping of tumor heterogeneities on clinical tissue specimens with multiplexed quantum dots. Jian Liu, Stephen K. Lau, Vijay A. Varma, Richard A. Moffitt, Matthew Caldwell, Tao Liu, Andrew N. Young, John A. Petros, Adeboye O. Osunkoya, Tracey Krogstad, Brian Leyland-Jones, May D. Wang, and Shuming Nie*. ACS Nano, 2010, 4(5), 2755-2765.

Patents：

1. Programable Sample-Loading Microfluidic Device Containing Three-Dimensional Structures. Liu, J., Ye, D., Zhou, L., Zuo, X., Fan, C., 201610524702.9 (CN)

2. A Method to Detect MMP Enzymatic Activities at the Single-cell Level Using Microdroplets. Liu, J., Yu, Z., 201610186024.X (CN)

3. A Method to Synthesize Microarrays of Nanoparticle Clusters as reproducible SERS Substrates, Liu, J., Ye, M., 201510120872.6 (CN)

4. Cell Ientification with Nanoparticles, Compositions and Methods Related Thereto, Nie, S., Liu, J., Brad, A.K., US 2013/0337471 A1

5. Microfluidic Chaotic Mixing for Nucleic Acid Hybridization. Liu, J., Williams, B.A., Wold, B.J., Quake, S.R., US2007/0054293A1