姓 名:苏玛
职称职务:助理研究员
电子邮箱:suma@suda.edu.cn
办公地址:云轩楼1430
一、学习工作经历
1、学历背景:
2010.9-2014.7 厦门大学,本科
2014.8-2018.12 美国南佛罗里达大学,博士(硕博连读)
2、工作经历:
2019.7至今 18新利体育
药学院,助理研究员
二、研究方向
1. 抗菌药的设计与合成。
2. 靶向炎症信号通路的小分子药物的设计与合成。
3. 多肽类药物的设计与合成。
三、主要研究成果
1.近年来发表SCI论文二十余篇,其中第一作者/通讯作者9篇。
(1) Ma Su, Donglin Xia, Peng Teng, Alekhya Nimmagadda, Chao Zhang, Timothy Odom, Annie Cao, Yong Hu, and Jianfeng Cai.* Membrane-Active Hydantoin Derivatives as Antibiotic Agents, J. Med. Chem., 2017, 60, 8456-8465.
( https://doi.org/10.1021/acs.jmedchem.7b00847)
Ma Su; Minghui Wang; Yuzhu Hong; Alekhya Nimmagadda; Ning Shen; Yan Shi; Ruixuan Gao; En Zhang; Chuanhai Cao; Jianfeng Cai*; Polymyxin derivatives as broad-spectrum antibiotic agents, Chemical Communications, 2019, 55: 13104-13107. ( https://doi.org/10.1039/C9CC06908A)
Ma Su; Yan Shi; Minghui Wang; Ruixuan Gao; Jianfeng Wu; Hai Xu; Chuanwu Xi; Jianfeng Cai*, The activity of small urea-γ-AApeptides toward Gram-positive bacteria, ChemMedChem, 2019, 14:1963-1967.
( https://doi.org/10.1002/cmdc.201900520)
Ma Su, Weiwei Wang, Feng Liu*, Huanqiu Li*, Recent progress on the discovery of NLRP3 inhibitors and their therapeutic potential, Current Medicinal Chemistry, 2020, 27, 1-14. DOI: 10.2174/0929867327666200123093544
Ma Su, Xingyu Gong, Feng Liu*, An update on the emerging approaches for histone deacetylase (HDAC) inhibitor drug discovery and future perspectives, Expert Opinion on Drug Discovery, 2021, 16, 745-761.
( https://doi.org/10.1080/17460441.2021.1877656)
Ma Su; Yifan Zhu; Wei Wang; Feng Liu*; Huanqiu Li* ; γ-AApeptides as a new class of peptidomimetics: Design, synthesis, and applications, Current Topics in Medicinal Chemistry, 2021, 21: 2574-2592. DOI: 10.2174/1568026621666210727160852
Wan Tang, Duan-Yang Yan, Kai-Cheng Liang, Ma Su*, Feng Liu*, Radical-mediated alkene carboamination/dearomatization of arylsulfonyl-o-allylanilines via photoredox catalysis, Organic Chemistry Frontier, 2022, 9 (23), 6535-6539.
( https://doi.org/10.1039/D2QO01221A)
Ma Su; Zhang Li; Duanyang Yan; Xingyue Ji; Feng Liu, Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters. Mini-Reviews in Medicinal Chemistry, 2023, 23, 1-31. DOI: 10.2174/1389557523666230427152234
Yating Chen; Zifan Ye; Wenteng Zhen; Lu Zhang; Xiangyang Min; Yipeng Wang*; Feng Liu*; Ma Su* ; Design and synthesis of broad-spectrum antimicrobial amphiphilic peptidomimetics to combat drug-resistance, Bioorganic Chemistry, 2023, 140: 106766. DOI: 10.1016/j.bioorg.2023.106766
参与专著撰写1部。
Privileged Scaffolds in Drug Discovery,Chapter 8, Indole and indoline scaffolds in drug discovery, ISBN: 978-0-443-18611-0.
主持江苏省自然科学青年项目1项:新型小分子抗耐药菌药物的设计与合成