Xiaoming ZHANG Ph.D.

时间: 2023-05-02 浏览次数: 13

Name:	Xiaoming ZHANG	Gender:	Male
Education:
Academic degree:	PhD	Academic title:	PI/Adjunct professor
Departments:	Unit of Innate Defense and Immune Modulation	Discipline:	Immunology
Phone:	021-54923130	E-mail:	xmzhang@ips.ac.cn
Mailing Address:	Life Science Research Building No. 320 Yueyang Road, Xuhui District, 200031

Curriculum vitae:
2004.10-2007.09:　Ph.D., Immunology, Pierre and Marie Curie (Pairs 6) University, France 2000.09-2003.07:　M.S., Biochemistry and Molecular Biology, Yangzhou University,China 2012.01- Professor, Principal Investigator, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China 2007.10- 2011.12: Postdoctoral Researcher, Institut Pasteur, France 2011, “1000-talents Plan” for young researchers by the General Office of the Central Committee of the Chinese Communist Party

Curriculum vitae:

2004.10-2007.09:　Ph.D., Immunology, Pierre and Marie Curie (Pairs 6) University, France

2000.09-2003.07:　M.S., Biochemistry and Molecular Biology, Yangzhou University,China

2012.01- Professor, Principal Investigator, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China

2007.10- 2011.12: Postdoctoral Researcher, Institut Pasteur, France

2011, “1000-talents Plan” for young researchers by the General Office of the Central Committee of the Chinese Communist Party

Research direction:
Innate Defense and Immune Modulation

Research direction:

Innate Defense and Immune Modulation

Research progress:
Publications： 1.Dong Z, Gong K, Huang D, Zhu W, Sun W, Zhang Y, Xin P, Shen Y, Wu P, Li J, Zhang XM, Wei MMyocardialinfarctionacceleratesglomerularinjury and microalbuminuria in diabetic rats via local hemodynamics and immunity. *Int J Cardiol,2015, 179:397-408. (: Corresponding author) 2. Zhang XM, Mozeleski B, Lemoine S, Dériaud E, Lim A, Zhivaki D, Azria E, Le Ray C, Roguet G, Launay O, Vanet A, Leclerc C, Lo-Man R. CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus. *SciTransl Med. 2014, 6(238):238ra72. 3. Zhang XM, Casartelli N, Lemoine S, Mozeleski B, Azria E, Le Ray C, Schwartz O, Launay O, Leclerc C, Lo-Man R. Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings. J Infect Dis. 2014, 210(3):424-434. 4. Zhang XM. Regulatory functions of innate-like B cells. Cell MolImmunol, 2013, 10(2): 113-121. 5. Zhang XM, Lepelley A, Azria A, Lebon P, Rouguet G, Schwartz O, Launay O, Leclerc C and Lo-Man R. Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses. Plos One, 2013, 8(1): e52003. 6. Freire T？, Zhang XM？, Deriaud E,Ganneau C, Vichier-Guerre S, Azria E, Launay O, Lo-Man R, Bay S, and Leclerc C. GlycosidicTn-based vaccines targetingdermal DC favor germinal center B celldevelopment and potentantibodyresponses in the absence of adjuvant. Blood, 2010, 116(18): 3526-3536. (？: equal contribution) 7. Zhang XM, Majlessi L, Deriaud E,Leclerc C and Lo-Man R. Coactivation of Syk kinase and MyD88 adaptorproteinpathways by bacteriapromotesregulatoryproperties of neutrophils. Immunity, 2009, 31 (5): 761-771. 8. Zhang XM, Deriaud E, Jiao XA, Braun D, Leclerc C and Lo-Man R. Type I interferonsprotectneonatesfrom acute inflammation through IL-10 producing B cells. J Exp Med*, 2007, 204(5): 1107-1118.

Research progress:

Publications：

1.Dong Z, Gong K, Huang D, Zhu W, Sun W, Zhang Y, Xin P, Shen Y, Wu P, Li J, Zhang XM*, Wei M*Myocardialinfarctionacceleratesglomerularinjury and microalbuminuria in diabetic rats via local hemodynamics and immunity. Int J Cardiol,2015, 179:397-408. (*: Corresponding author)

2. Zhang XM, Mozeleski B, Lemoine S, Dériaud E, Lim A, Zhivaki D, Azria E, Le Ray C, Roguet G, Launay O, Vanet A, Leclerc C, Lo-Man R. CD4 T cells with effector memory phenotype and function develop in the sterile environment of the fetus. SciTransl Med. 2014, 6(238):238ra72.

3. Zhang XM, Casartelli N, Lemoine S, Mozeleski B, Azria E, Le Ray C, Schwartz O, Launay O, Leclerc C, Lo-Man R. Plasmacytoid dendritic cells engagement by influenza vaccine as a surrogate strategy for driving T-helper type 1 responses in human neonatal settings. J Infect Dis. 2014, 210(3):424-434.

4. Zhang XM. Regulatory functions of innate-like B cells. Cell MolImmunol, 2013, 10(2): 113-121.

5. Zhang XM, Lepelley A, Azria A, Lebon P, Rouguet G, Schwartz O, Launay O, Leclerc C and Lo-Man R. Neonatal plasmacytoid dendritic cells (pDCs) display subset variation but can elicit potent anti-viral innate responses. Plos One, 2013, 8(1): e52003.

6. Freire T？, Zhang XM？, Deriaud E,Ganneau C, Vichier-Guerre S, Azria E, Launay O, Lo-Man R, Bay S, and Leclerc C. GlycosidicTn-based vaccines targetingdermal DC favor germinal center B celldevelopment and potentantibodyresponses in the absence of adjuvant. Blood, 2010, 116(18): 3526-3536. (？: equal contribution)

7. Zhang XM, Majlessi L, Deriaud E,Leclerc C and Lo-Man R. Coactivation of Syk kinase and MyD88 adaptorproteinpathways by bacteriapromotesregulatoryproperties of neutrophils. Immunity, 2009, 31 (5): 761-771.

8. Zhang XM, Deriaud E, Jiao XA, Braun D, Leclerc C and Lo-Man R. Type I interferonsprotectneonatesfrom acute inflammation through IL-10 producing B cells. J Exp Med, 2007, 204(5): 1107-1118.