报告题目：Analysis of NG2 glia differentiation in health and disease

报告人： Frank Kirchhoff 教授

报告时间：2013年9月23日（周一）上午10：00

报告地点：18新利体育 神经18新利备用网站 所会议室

报告人简介：

Frank Kirchhoff 教授

Affiliation：Full Professor (W3) and Head of the Department of Molecular Physiology, Institute of Physiology, University of Saarland

Honours, Distinctions and Community Services

1987-1989   PhD Fellowship of the Boehringer Ingelheim Fonds

1981-1986   Fellowship of the Studienstiftung des deutschen Volkes

Since 2009   Editorial board member of GLIA

Since 2010   Editorial board member of Journal of Chemical Neuroanatomy

Since 2013   coordinator of the DFG Priority Programme “Gial Heterogeneity”

Research Interests

His research focuses on the molecular and cellular mechanisms of neuron-glia interaction in the central nervous system. They are pursuing the following research questions: How do glial transmitter receptors sense and modulate synaptic transmission? What is the impact for living organisms? How do glial cells respond to acute injuries within the central nervous system?

Publications

1. Saab AS, Neumeyer A, Jahn HM, Cupido A, Šimek AAM, Boele HJ, Scheller A, Le Meur K, Götz M, Monyer H, Sprengel R, Rubio ME, Deitmer JW, De Zeeuw CI and Kirchhoff F (2012) Bergmann Glial AMPA Receptors are Re-quired for Fine Motor Coordination. Science 337:749-53

2. Lioy DT, Garg SK, Monaghan CE, Raber J, Foust KD, Kaspar BK, Hirrlinger PG, Kirchhoff F, Bissonnette JM, Ballas N and Mandel G. (2011) A role for glia in the progression of Rett's syndrome. Nature 475: 497-500.

3. Hirrlinger J, Scheller A, Hirrlinger PG, Kellert B, Tang W, Wehr MC, Goebbels S, Reichenbach A, Sprengel R, Rossner MJ and Kirchhoff F (2009) Split-cre complementation indicates coincident activity of different genes in vivo. Plos One 4:e4286.

4. Hirrlinger PG, Scheller A, Braun C, Hirrlinger J and Kirchhoff F (2006) Temporal control of gene recombination in astrocytes by transgenic expression of the tamoxifen-inducible DNA recombinase variant CreERT2. Glia 54:11-20.

5. Nimmerjahn A, Kirchhoff F and Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314-1318.