Dr. Liangzhu Feng

Assistant Researcher

Professional  Activity                                      

2018/07 -         Associate Researcher, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University

2016/11 -2018/06  Assistant Researcher, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University

2015/10 -2016/10  Post-doctoral fellow, Institute of Chinese Medical Science (ICMS), University of Macau

Education  Backgrorud                                     

2010/09 - 2015/06  Ph.D., Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University

2013/09 - 2014/10  Joint-training Ph.D. Program (supported by China ScholarshipCouncil), Department of Biomedical Engineering, Georgia Institute of Technology

2006/08 - 2010/06  Bachelor, School of Biology & Basic Medical Sciences,

Soochow University

Research Experience and Accomplishments

Dr. Liangzhu Feng focused his researchs on the development of functional nanobiomaterials for the modulation of tumor microenvironment and innovative cancer treatment. Starting from 2011, Dr. Feng has authored over 90 peer-reviewed papers, which have received a total citation of > 11, 000 times and given him an H-index at 51. He was listed as one of the ‘Highly Cited Researchers (Chemistry, Materials)’ by Clarivate Analytics in 2019. Dr. Feng also served as the invited reviewers for numerous academic journals, such as Nature Communication, ACS Nano, Nano Letters, Theranostics, Biomaterials, Journal of Controlled Release.

Representative Publications:

[18] Yujie Zhu, Zhijuan Yang, Ziliang Dong, Yimou Gong, Yu Hao, Longlong Tian, Xianzhu Yang, Zhuang Liu*, Liangzhu Feng*, “CaCO₃-Assisted Preparation of pH-Responsive Immune-Modulating Nanoparticles for Augmented Chemo-Immunotherapy” Nano-Micro Lett. 2021, 13(1),1-18.

[17] Ziliang Dong, Yu Hao, Quguang Li, Zhijuan Yang, Yujie Zhu, Zhuang Liu, Liangzhu Feng*, “Metal-polyphenol-network coated CaCO₃ as pH-responsive nanocarriers to enable effective intratumoral penetration and reversal of multidrug resistance for augmented cancer treatments” Nano Res. 2020, 13, 3057–3067.

[16] Ziliang Dong, Liangzhu Feng*, Yu Hao, Quguang Li, Muchao Chen, Zhijuan Yang, He Zhao, Zhuang Liu*, “Synthesis of CaCO₃-Based Nanomedicine for Enhanced Sonodynamic Therapy via Amplification of Tumor Oxidative Stress” Chem 2020, 6(6), 1391-1407.

[15] Ziliang Dong, Liangzhu Feng*, Yu Chao, Yu Hao, Muchao Chen, Fei Gong, Xiao Han, Rui Zhang, Liang Cheng, Zhuang Liu*, “Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy” Nano Lett. 2019, 19, 805-815

[14] Ziliang Dong, Liangzhu Feng*, Yu Hao, Muchao Chen, Min Gao, Yu Chao, He Zhao, Wenwen Zhu, Jingjing Liu, Chao Liang, Qiao Zhang, and Zhuang Liu*, Synthesis of Hollow Biomineralized CaCO3-Polydopamine Nanoparticles for Multimodal Imaging-Guided Cancer Photodynamic Therapy with Reduced Skin Photosensitivity, J. Am. Chem. Soc., 2018, 140, 2165–2178

[13] Danlei Tao, Liangzhu Feng*, Yu Chao, Chao Liang, Xuejiao Song, Hairong Wang, Kai Yang, Zhuang Liu*, “Covalent Organic Polymers Based on Fluorinated Porphyrin as Oxygen Nano-Shuttles for Tumor Hypoxia Relief and Enhanced Photodynamic Therapy” Adv. Funct. Mater. 2018, 28, 1804901

[12] Liangzhu Feng#, Ziliang Dong#, Chao Liang, Muchao Chen, Danlei Tao, Liang Cheng, Kai Yang, Zhuang Liu*, “Iridium Nanocrystals Encapsulated Liposomes as Near-Infrared Light Controllable Nanozymes for Enhanced Cancer Radiotherapy” Biomaterials, 2018, 181, 81-91

[11]Yicheng Zhang, Liangzhu Feng*, Jun Wang, Danlei Tao, Chao Liang, Liang Cheng, Erhong Hao*, Zhuang Liu*, “Surfactant‐Stripped Micelles of Near Infrared Dye and Paclitaxel for Photoacoustic Imaging Guided Photothermal‐Chemotherapy” Small, 2018, 14, 1802991 

[10] Rui Zhang, Liangzhu Feng*, Ziliang Dong, Li Wang, Chao Liang, Jiawen Chen, Qingxi Ma, Qian Chen, Yucai Wang, Zhuang Liu*, Glucose & Oxygen Exhausting Liposomes for Combined Cancer Starvation and Hypoxia-Activated Therapy, Biomaterials, 2018, 162, 123-131.

[9] Liangzhu Feng, Ziliang Dong, Danlei Tao, Yicheng Zhang, Zhuang Liu*, The acidic tumor microenvironment: a target for smart cancer nano-theranostics, Natl. Sci. Rev., 2018, 5, 269-286,

[8] Liangzhu Feng, Liang Cheng, Ziliang Dong, Danlei Tao, Meiwan Chen*, Zhuang Liu*, Theranostic Liposomes with Hypoxia-Activated Prodrug to Effectively Destruct Hypoxic Tumors post Photodynamic Therapy, ACS Nano, 2017, 11, 927-937

[7] Rui Zhang, Xuejiao Song, Chao Liang, Xuan Yi, Guosheng Song, Yu Chao, Yu Yang, Kai Yang, Liangzhu Feng*, Zhuang Liu*, Catalase-loaded cisplatin-prodrug-constructed liposomes to overcome tumor hypoxia for enhanced chemo-radiotherapy of cancer, Biomaterials, 2017, 138, 13-21.

[6] Liangzhu Feng, Danlei Tao, Ziliang Dong, Qian Chen, Yu Chao, Zhuang Liu*, Meiwan Chen*, Near-infrared Light Activation of Quenched Liposomal Ce6 for Synergistic Cancer Phototherapy with Effective Skin Protection, Biomaterials, 2017, 127, 13-24

[5] Liangzhu Feng, Min Gao, Danlei Tao, Qian Chen, Hairong Wang, Ziliang Dong, Meiwan Chen,* and Zhuang Liu*, Cisplatin-Prodrug-Constructed Liposomes as a Versatile Theranostic Nanoplatform for Bimodal Imaging Guided Combination Cancer Therapy, Adv. Funct. Mater., 2016, 26, 2207-2217

[4] Ziliang Dong, Liangzhu Feng*, Wenwen Zhu, Xiaoqi Sun, Min Gao, He Zhao, Yu Chao, Zhuang Liu*, CaCO₃ Nanoparticles as an Ultra-sensitive Tumor-pH-Responsive Nanoplatform Enabling Real-Time Drug Release Monitoring and Cancer Combination Therapy, Biomaterials, 2016, 110, 60-70

[3] Guangbao Yang, Jingjing Liu, Yifan Wu, Liangzhu Feng*, Zhuang Liu*, Near-infrared-light responsive nanoscale drug delivery systems for cancer treatment, Coord. Chem. Rev., 2016, 320-321, 100-117.

[2] Liangzhu Feng#, Xianzhu Yang#, Xiaoze Shi, Xiaofang Tan, Rui Peng, Jun Wang*, Zhuang Liu*, Polyethylene glycol and polyethylenimine dual functionalized nano-graphene oxide for photothermally enhanced gene delivery, Small, 2013, 9 (11), 1989-1997

[1] Liangzhu Feng, Shuai Zhang, Zhuang Liu*, Graphene based gene transfection, Nanoscale, 2011, 3 (3), 1252-1257

Publication /Citation List:

https://scholar.google.com/citations?user=MkQwgDsAAAAJ&hl=en

Contact：0512-65880927

E-mail: lzfeng@suda.edu.cn