冯良珠

博士，教授

       2010年于18新利体育 基础医学与生命科学学院获理学学士学位；2015年于18新利体育 功能纳米与软物质研究院获理学博士学位，期间获“国家留学基金委公派研究生项目”资助，于2013年9月—2014年10月赴美国佐治亚理工学院生物工程系访学；2015年10月—2016年10月于澳门大学中华医药研究院从事博士后研究。2016年11月加入18新利体育 功能纳米与软物质研究院任助理研究员；2018年7月晋升为副研究员，同年入选“18新利体育 优秀青年学者”；2022年7月晋升为研究员。

研究领域：

1. 仿生纳米载体与肿瘤靶向药物递送

2. 生物催化材料与肿瘤生物催化治疗

3. 金属离子载体与肿瘤离子干扰治疗

4. 肿瘤微环境调控与序贯性联合治疗

主要学术成果：    

      冯良珠博士的研究兴趣集中在功能化纳米药物载体/生物材料的构建、肿瘤微环境调节与新型肿瘤联合治疗等方面。迄今在Science Advances, Nature Communications, Chem, J. Am. Chem. Soc., Adv. Mater.等高水平学术期刊上发表论文110余篇，文章的总他引17000余次，SCI H-index为58；两次入选美国美国科睿唯安公布的“全球高被引科学家名单”（Highly Cited Researchers，交叉领域，2019、2021年）；主持/参与国自然面上项目、科技部重点研发计划，江苏省优秀青年基金等项目资助。

荣誉奖励：

2022   江苏省优秀青年基金

2021   科睿唯安-全球高被引科学家（交叉学科）

2019   科睿唯安-全球高被引科学家（交叉学科）

2016   江苏省科学技术一等奖 （排名第五）

学术兼职：

Young Editorial Board Members, BMEMat (2022-)

ECR board member, Materials Today Bio (IF = 10.761, Q1, 2022-)

Editorial board member, Nanomaterials (IF = 5.719, Q1, 2021- )

代表性论文：

[20] Yujie Zhu, Zhijuan Yang, Zijian Pan, Yu Hao, Chunjie Wang, Ziliang Dong, Quguang Li, Yikai Han, Longlong Tian, Liangzhu Feng*, Zhuang Liu* Metallo-alginate hydrogel can potentiate microwave tumor ablation for synergistic cancer treatment. Sci. Adv., 2022, 8(31), abo5285 

[19]Yu Hao, Lei Zhang, Ziliang Dong, Chunjie Wang, Yu Chao, Dongxu Zhao, Yujie Zhu, Zhijuan Yang, Nailin Yang, Yikai Han, Liangzhu Feng, Zhuang Liu, Percutaneous implantation of ethanol fueled catalytic hydrogel suppresses tumor growth by triggering ferroptosis, Mater. Today, 2022, 55, 7-20.

[18] Yang, Zhijuan, Zhu, Yujie, Dong, Ziliang, Hao, Yu, Wang, Chunjie, Li, Quguang, Wu, Yumin, Feng, Liangzhu*, Liu, Zhuang*, Engineering bioluminescent bacteria to boost photodynamic therapy and systemic anti-tumor immunity for synergistic cancer treatment. Biomaterials, 2022, 281, 121332.

[17] Wang, Chunjie, Dong, Ziliang, Hao, Yu, Zhu, Yujie, Ni, Jing, Li, Quguang, Liu, Bo, Han, Yikai, Yang, Zhijuan, Wan, Jianmei, Yang, Kai, Liu, Zhuang*, Feng, Liangzhu*, Coordination Polymer-Coated CaCO₃ Reinforces Radiotherapy by Reprogramming the Immunosuppressive Metabolic Microenvironment. Adv. Mater., 2022, 34, 3.

[16] Yang, Zhijuan, Zhu, Yujie, Dong, Ziliang, Li, Wei, Yang, Nailin, Wang, Xianwen, Feng, Liangzhu*, Liu, Zhuang, Tumor-killing nanoreactors fueled by tumor debris can enhance radiofrequency ablation therapy and boost antitumor immune responses. Nat. Commun., 2021, 12, 1.

[15] Li, Quguang, Dong, Ziliang, Chen, Meiwan* and Feng, Liangzhu*, Phenolic molecules constructed nanomedicine for innovative cancer treatment. Coord. Chem. Rev., 2021, 439.

[14] Yujie Zhu, Zhijuan Yang, Ziliang Dong, Yimou Gong, Yu Hao, Longlong Tian, Xianzhu Yang, Zhuang Liu*, Liangzhu Feng*, “CaCO₃-Assisted Preparation of pH-Responsive Immune-Modulating Nanoparticles for Augmented Chemo-Immunotherapy” Nano-Micro Lett. 2021, 13(1),1-18.

[13] Ziliang Dong, Yu Hao, Quguang Li, Zhijuan Yang, Yujie Zhu, Zhuang Liu, Liangzhu Feng*, “Metal-polyphenol-network coated CaCO₃ as pH-responsive nanocarriers to enable effective intratumoral penetration and reversal of multidrug resistance for augmented cancer treatments” Nano Res. 2020, 13, 3057–3067.

[12] Ziliang Dong, Liangzhu Feng*, Yu Hao, Quguang Li, Muchao Chen, Zhijuan Yang, He Zhao, Zhuang Liu*, “Synthesis of CaCO₃-Based Nanomedicine for Enhanced Sonodynamic Therapy via Amplification of Tumor Oxidative Stress” Chem 2020, 6(6), 1391-1407.

[11] Ziliang Dong, Liangzhu Feng*, Yu Chao, Yu Hao, Muchao Chen, Fei Gong, Xiao Han, Rui Zhang, Liang Cheng, Zhuang Liu*, “Amplification of Tumor Oxidative Stresses with Liposomal Fenton Catalyst and Glutathione Inhibitor for Enhanced Cancer Chemotherapy and Radiotherapy” Nano Lett. 2019, 19, 805-815

[10] Ziliang Dong, Liangzhu Feng*, Yu Hao, Muchao Chen, Min Gao, Yu Chao, He Zhao, Wenwen Zhu, Jingjing Liu, Chao Liang, Qiao Zhang, and Zhuang Liu*, Synthesis of Hollow Biomineralized CaCO3-Polydopamine Nanoparticles for Multimodal Imaging-Guided Cancer Photodynamic Therapy with Reduced Skin Photosensitivity, J. Am. Chem. Soc., 2018, 140, 2165–2178

[9] Danlei Tao, Liangzhu Feng*, Yu Chao, Chao Liang, Xuejiao Song, Hairong Wang, Kai Yang, Zhuang Liu*, “Covalent Organic Polymers Based on Fluorinated Porphyrin as Oxygen Nano-Shuttles for Tumor Hypoxia Relief and Enhanced Photodynamic Therapy” Adv. Funct. Mater. 2018, 28, 1804901

[8] Liangzhu Feng#, Ziliang Dong#, Chao Liang, Muchao Chen, Danlei Tao, Liang Cheng, Kai Yang, Zhuang Liu*, “Iridium Nanocrystals Encapsulated Liposomes as Near-Infrared Light Controllable Nanozymes for Enhanced Cancer Radiotherapy” Biomaterials, 2018, 181, 81-91

[7]Yicheng Zhang, Liangzhu Feng*, Jun Wang, Danlei Tao, Chao Liang, Liang Cheng, Erhong Hao*, Zhuang Liu*, “Surfactant‐Stripped Micelles of Near Infrared Dye and Paclitaxel for Photoacoustic Imaging Guided Photothermal‐Chemotherapy” Small, 2018, 14, 1802991  

[6] Liangzhu Feng, Ziliang Dong, Danlei Tao, Yicheng Zhang, Zhuang Liu*, The acidic tumor microenvironment: a target for smart cancer nano-theranostics, Natl. Sci. Rev., 2018, 5, 269-286,

[5] Liangzhu Feng, Danlei Tao, Ziliang Dong, Qian Chen, Yu Chao, Zhuang Liu*, Meiwan Chen*, Near-infrared Light Activation of Quenched Liposomal Ce6 for Synergistic Cancer Phototherapy with Effective Skin Protection, Biomaterials, 2017, 127, 13-24

[4] Liangzhu Feng, Min Gao, Danlei Tao, Qian Chen, Hairong Wang, Ziliang Dong, Meiwan Chen,* and Zhuang Liu*, Cisplatin-Prodrug-Constructed Liposomes as a Versatile Theranostic Nanoplatform for Bimodal Imaging Guided Combination Cancer Therapy, Adv. Funct. Mater., 2016, 26, 2207-2217

[3] Ziliang Dong, Liangzhu Feng*, Wenwen Zhu, Xiaoqi Sun, Min Gao, He Zhao, Yu Chao, Zhuang Liu*, CaCO₃ Nanoparticles as an Ultra-sensitive Tumor-pH-Responsive Nanoplatform Enabling Real-Time Drug Release Monitoring and Cancer Combination Therapy, Biomaterials, 2016, 110, 60-70

[2] Liangzhu Feng#, Xianzhu Yang#, Xiaoze Shi, Xiaofang Tan, Rui Peng, Jun Wang*, Zhuang Liu*, Polyethylene glycol and polyethylenimine dual functionalized nano-graphene oxide for photothermally enhanced gene delivery, Small, 2013, 9 (11), 1989-1997

[1] Liangzhu Feng, Shuai Zhang, Zhuang Liu*, Graphene based gene transfection, Nanoscale, 2011, 3 (3), 1252-1257

发表论文列表：

https://scholar.google.com/citations?user=MkQwgDsAAAAJ&hl=en

联系方式：0512-65880927

E-mail: lzfeng@suda.edu.cn