单位: 摘要: | Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology Soochow University , Suzhou , Jiangsu 215123 , China A new “Abraxane-like” nanotheranostic formulation self-assembled from three clinically approved agents, human serum albumin, paclitaxel, and indocyanine green, is developed. Utilizing such a newly formulated nanodrug, combined photothermal and chemotherapy is conducted under the guidance of imaging, not only effectively eliminating subcutaneous tumors, but also significantly inhibiting the development of metastatic tumors in this proof-of-concept study. |