报告题目：Manufacturing of Artificial Tissues using Hybrid Biomaterials and a Low-Cost Three Dimensional Printer
报告时间：2016年11月14日（星期一）下午15:00-16:00 报告地点：18新利体育
南区1号楼3楼骨科研究所317学术报告厅 报告人：Dr.David A. Stout,Assistant professor, California State University, USA Abstract Tissue engineering has a significant impact on how organs are created, yet scaffolding and vascularization are still an issue. Our novel methods of dispensing biomaterials utilize current technologies to efficiently make three dimensional tissue. By using a low-cost RepRap Prusa i3, we have modified the system for our manufactured biomaterial. Modifications include a pneumatic system, a miniature incubator, and a syringe-like nozzle. Bounded by a water-jacket, the incubator serves as a cartridge to maintaining homeostasis of the biomaterial and the cell injected. The pneumatic pump pushes the biomaterials through a Teflon tube into the syringe nozzle which moves across the z-axis. The nozzle dispenses accurate droplets or tubules using the accompanying client software. What constitutes the microenvironment of the cell is alginate. This hydrogel is derived from brown seaweed that contains a rich Extra Cellular Matrix (ECM) which can hold water and nutrients. Although it has been the most reliable biomaterial in the industry, the ECM is not stable to contain cells. To solve this, Ethylenediaminetetraacetic acid acts as an adhesive for the cells to attach to the alginate gel. Studies suggest that when cells are controlled, they will be influenced to make the appropriate tissue necessary to create the structures necessary for an organ. Biography Dr. David A. Stout is an assistant professor with a joint appointment in the Department of Mechanical and Aerospace Engineering and in the Department of Biomedical Engineering at California State University, Long Beach. He received his B.S. degree in Aerospace Engineering with a minor in Chemistry from California State University, Long Beach in 2010, and a Ph.D. from Brown University in Biomedical Engineering in 2014. Currently, Dr. Stout is the founding director of the Long Beach Bioengineering Laboratory at California State University, Long Beach, a BSL-2 facility, where he oversees all research projects-ranging from nano-cardivascular research to contraceptive design to 3D tissue printing. Additionally, he is the founding member of the new Department of Biomedical Engineering at CSULB. Dr. Stout‘s main research focus is applying engineering techniques to the biomedical world to combat some of the most deadly diseases and infections. His research expertise is in cardiovascular biomaterials, orthopedic biomaterials, nano-medicine, solid mechanics, cell mechanics and migration.
