胡文涛,副教授
电话:0512-65882451
电子邮箱:wthu@suda.edu.cn
通讯地址:苏州市工业园区仁爱路199号, 邮编215123
个人简历:
2006年毕业于兰州大学生物系,获理学学士学位。2013年毕业于中国科学院大学,获粒子物理与原子核物理专业博士学位。博士期间受国家留学基金委资助赴新泽西肿瘤研究所联合培养一年。2013年7月至2016年7月于中国科学院近代物理研究所任助理研究员,2016年8月起加入18新利体育 医学部放射医学与防护学院。作为项目负责人主持国家重点研发计划子课题一项、国家自然科学基金青年基金一项、载人航天预研项目一项、中国科学院“西部之光”项目一项,作为骨干人员参加了包括973计划、国家自然科学基金重点项目在内的多个项目。在国内外核心期刊发表文章五十余篇。
研究方向:
1. 空间辐射致肿瘤发生的分子机制;
2. 非编码RNA与辐射生物学效应;
3.空间多种环境因素的复合生物学效应。
科研项目:
1. 国家重点研发计划“数字诊疗装备研发”子课题,2018YFC0115705,多线束放疗高灵敏伴随诊断和疗效评估方法研究,2018/08-2021/07,15万元,主持。
2. 国家自然科学基金青年科学基金项目,11405235,RAC2基因辐射诱导表达对黑色素瘤细胞辐射敏感性的影响,2015/01-2017/12,28万元,主持。
3. 中国科学院“西部之光”项目,Y463040XBB,空间辐射诱导的旁观者效应通过诱导肺部EMT促使肺癌发生,2014/01-2016/12,20万元,主持。
代表性论著:
1. Wentao Hu#, Lin Zhu#, Weiwei Pei#, Shuxian Pan, Ziyang Guo, Anqing Wu, Hailong Pei, Jing Nie, Bingyan Li, Yoshiya Furusawa, Teruaki Konishi, Tom K. Hei*, Guangming Zhou*. Overexpression of ras-related C3 botulinum toxin substrate 2 radiosensitizes melanoma cells in vitro and in vivo. Oxidative medicine and cellular longevity. 2019: 5254798.
2. Wentao Hu, Xuelian Wei, Lin Zhu, Dong Yin, Aimin Wei, Xiangyu Bi, Tao Liu, Guangming Zhou, Yinghuai Qiang, Xuhui Sun, Zhen Wen*, Yue Pan*. Enhancing proliferation and migration of fibroblast cells by electric stimulation based on triboelectric nanogenerator. Nano Energy, 2019, 57(2019): 600-607.
3. Weiwei Pei#, Jiayao Chen#, Chao Wang, Suhao Qiu, Jianfeng Zeng, Mingyuan Gao, Bin Zhou, Dan Li, Michael S. Sacks, Lin Han, Hong Shan*, Wentao Hu*, Yuan Feng*, Guangming Zhou*. Regional biomechanical imaging of liver cancer cells. Journal of Cancer, 2019, 10(19): 4481-4487.
4. Wentao Hu#, Weiwei Pei#, Lin Zhu, Jing Nie, Hailong Pei, Jian Zhang, Bingyan Li, Tom K. Hei*, Guangming Zhou*. Microarray profiling of TGF-β1-induced long non-coding RNA expression patterns in human lung bronchial epithelial BEAS-2B cells. Cellular Physiology and Biochemistry, 2018, 50(6): 2071-2085.
5. Hong Dai, Junchao Feng, Huahui Bian, Weibo Chen, Youyou Wang, Yulong Liu*, Wentao Hu*. Complete technical scheme for automatic biological dose estimation platform. Dose-Response, 2018, 16(4): 1559325818799951.
6. Wentao Hu#, Hailong Pei#, Fang Sun, Pengfei Li, Jing Nie, Bingyan Li, Tom K. Hei, Guangming Zhou*. Epithelial-mesenchymal transition in non-targeted lung tissues of Kunming mice exposed to X-rays is suppressed by celecoxib. Journal of Radiation Research, 2018, 59(5): 583-587.
7. Huahui Bian, Youyou Wang, Weibo Chen, Yusong Zhang, Zhixiang Zhuang, Rui Xia, Hong Dai, Junchao Feng, Wangyang Pu, Lei Chen, Wu Cai, Wentao Hu*, Yulong Liu*. Multiple organ lesions in a case of contamination with multiple radionuclides after 38 years. Dose-Response, 2018, 16(4): 1559325818815019.
8. Wentao Hu, Shuai Xu, Bin Yao, Mei Hong, Xin Wu, Hailong Pei, Lei Chang, Nan Ding, Xiaofei Gao, Caiyong Ye, Jufang Wang, Tom K. Hei*, Guangming Zhou*. miR-663 inhibits radiation-induced bystander effects by targeting TGFB1 in a feedback mode. RNA Biology, 2014, 11(9): 1189-1198.
9. Wentao Hu#, Hailong Pei#, He Li, Nan Ding, Jinpeng He, Jufang Wang, Yoshiya Furusawa, Ryoichi Hirayama, Yoshitaka Matsumoto, Cuihua Liu, Yinghui Li, Tetsuya Kawata, Guangming Zhou*. Effects of shielding on the induction of 53BP1 foci and micronuclei after Fe ion exposures. Journal of Radiation Research, 2014, 55(1): 10-16.