李桢

日期:2020-03-30人气:619

李桢,博士生导师、特聘教授

中组部xxx人才

电子邮箱:zhenli[AT]suda.edu.cn

通讯地址:苏州工业园区仁爱路199, 邮编215123

  

2005年博士毕业于中国科学院化学研究所,先后在英国利物浦大学、德国锡根大学、澳大利亚昆士兰大学和澳大利亚卧龙岗大学担任助理研究员、洪堡学者、以及研究员。2006年入选德国洪堡学者,2009年入选澳大利亚Queensland Smart Futures Fellow2014年被聘为江苏省“特聘教授”,获得北京市科学技术一等奖(排名第二),2016年入选中组部人才计划、江苏省人才计划。自2014年加入18新利体育 放射医学与防护学院至今,开展多模态分子影像在重大疾病精准诊断与精准治疗中应用的相关研究。先后主持中央组织部人才项目1项,国家自然科学基金面上项目2项,国家科技部重点研发计划纳米科技重点专项子课题1项,国家自然科学基金重大科研仪器研制项目子课题1项,江苏省重点研发计划(社会发展-临床前沿技术)1项,江苏省人才项目3项。目前已申请专利10项,转让2项,撰写英文专著2章,发表SCI论文140余篇(其中60%论文发表在影响因子大于5的国际期刊,影响因子>10的论文40余篇),论文被引7400余次(单篇引用超过100次的有20篇)。担任国家自然科学基金委、Australian Research Council (ARC)等项目评审专家,以及Adv. Mater., Angew. Chem. Int. Ed., ACS Nano, Nano Lett 50余种知名杂志的审稿人。

 

学习经历:

1995-1999    中国石油大学(华东)应用化学专业(本科)

1999-2002    中国科学院成都有机化学研究所高分子物理与化学专业(硕士)

2002-2005    中国科学院化学研究所物理化学专业(博士)

 

研究方向:

多模态诊疗一体化分子影像探针的构建

多模态分子影像在肿瘤诊断与治疗中的应用

多模态分子影像在神经疾病诊断与治疗中的应用

  

代表性论文:

1. Engineering NIR-IIb Fluorescence of Er-Based Lanthanide Nanoparticles for Through-skull Targeted Imaging and Imaging-guided Surgery of Orthotopic Glioma

F. Ren, H. H. Liu, H. Zhang, Z. L. Jiang, B. Xia, C. Genevois, T. He, M. Allix, Q. Sun, Z. Li*, M. Y. Gao

Nano Today, 2020, NANTOD_100905.

2. Boosting H2O2-Guided Chemodynamic Therapy of Cancer by Enhancing Reaction Kinetics through Versatile Biomimetic Fenton Nanocatalysts and the Second Near-Infrared Light Irradiation

T. T. Wang, H. Zhang, H. H. Liu, Q. Yuan, F. Ren, Y. B. Han, Q. Sun, Z. Li*, M. Y. Gao

Adv. Funct. Mater., 2020, 30, 1906128.

3. Boosting Often Overlooked Long Wavelength Emissions of Rare-Earth Nanoparticles for NIR-II Fluorescence Imaging of Orthotopic Brain Tumor

Z. Liu, F. Ren, H. Zhang, Q. Yuan, Z. L. Jiang, H. H. Liu, Q. Sun, Z. Li*

Biomaterials, 2019, 219, 119364.

4. Boosting the Radiosensitizing and Photothermal Performance of Cu2-xSe Nanocrystals for Synergetic Radiophotothermal Therapy of Orthotopic Breast Cancer

Q. Huang, S. H. Zhang, H. Zhang, Y. B. Han, H. H. Liu, F. Ren, Q. Sun, Z. Li*

ACS Nano, 2019, 13, 1342-1353.

5. Monitoring the Opening and Recovery of the Blood-Brain-Barrier with Non-invasive Molecular Imaging by Biodegradable Ultra**all Cu2-xSe Nanoparticles

H. Zhang, T. T. Wang, W. B. Qiu, Y. B. Han, Q. Sun, J. F. Zeng, F. Yan, H. R. Zheng, Z. Li*, M. Y. Gao

Nano Lett, 2018, 18, 4985-4992.

6. Ultra-**all Nanocluster Mediated Synthesis of Nd-doped Core-Shell Nanocrystals with Emission in the Second Near-Infrared Window for Multimodal Imaging of Tumor Vasculature

F. Ren, L. H. Ding, H. H. Liu, Q. Huang, H. Zhang, L. J. Zhang, J. F. Zeng, Q. Sun, Z. Li*, M. Y. Gao

Biomaterials, 2018, 175, 30-43.

7. Ultra-Small Magnetic CuFeSe2 Ternary Nanocrystals for Multimodal Imaging Guided Photothermal Therapy of Cancer

X. X. Jiang, S. H. Zhang, F. Ren, L. Chen, J. F. Zeng, M. Zhu, Z. X. Cheng, M. Y. Gao, Z. Li*

ACS Nano, 2017, 11, 5633-5645.

8. Ambient Aqueous Synthesis of Ultra-**all PEGylated Cu2−xSe Nanoparticles as a Multifunctional Theranostic Agent for Multimodal Imaging Guided Photothermal Therapy of Cancer

S. H. Zhang, C. X. Sun, J. F. Zeng, G. L. Wang, Y. Wang, Q. Sun, Y. Wu, M. Y. Gao, S. X. Dou, Z. Li*

Adv. Mater., 2016, 28, 8927-8936.

9.Ultra**all Biocompatible WO3-x Nanodots for Multi-modality Imaging and Combined Therapy of Cancers

L. Wen, L. Chen, S. M. Zheng, J. F. Zeng, G. X. Duan, Y. Wang, G. L. Wang, Z. F. Chai, Z. Li*, M. Y. Gao*

Adv. Mater., 2016, 28, 5072-5079.

10.Ultra**all Biocompatible Bi2Se3 Nanodots for Multimodal Imaging-Guided Synergistic Radiophotothermal Therapy against Cancer

F. X. Mao, L. Wen, C. Sun, S. Zhang, G. Wang, J. Zeng, Y. Wang, J. M. Ma*, M. Y Gao, Z. Li*

ACS Nano, 2016, 10, 11145–11155.






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