裴海龙,博士,副教授,硕士生导师

 

  电话:0512-65882451

 

  电子邮箱:hlpei@suda.edu.cn

 

  通讯地址:苏州工业园区仁爱路199, 邮编215123

 

个人简介:

 

2010年毕业于西北大学生命科学学院生命科学与技术(基地班)获得理学学士学位。2015年毕业于中国科学院近代物理研究所,获生物物理学博士学位。攻读博士学位期间,在日本国立放射线医学综合研究所、北京大学医学、中国科学院生物物理研究所蛋白质国家研究中心参与合作交流,完成博士论文工作。20158月起加入18新利体育 医学部放射医学与防护学院。主要从事放射生物学、放射医学和空间生命科学的研究工作。作为项目负责人主持国家自然科学基金、中国博士后基金、江苏省科技计划项目等资助;作为主要人员参加包括973计划、国家自然科学基金重点项目、中国科学院先导专项等多个项目。以第一作者/通讯作者在Cancer ResearchOncogeneCell CycleJournal of Radiation Research等国内外知名期刊发表文章十余篇。

 

研究方向:

 

    1. 非编码RNA和辐射生物效应

    2. 细胞骨架动力学调控机制

    3. 线粒体稳态与自噬

 

科研项目:

 

    1. 国家自然科学基金-面上项目。82073480。主持。

    2. 国家自然科学基金-青年科学基金项目。81602794。主持。

    3. 江苏省基础研究计划(自然科学基金)-青年基金项目,BK20160334。主持。

    4. 中国博士后科学基金第59批面上资助,2016M591904。主持。

    5. 中国博士后科学基金第十批特别资助,2017T100399。主持。

    6. 国家自然科学基金-面上项目。82073480。主持。

 

社会服务:

 

    中国环境诱变剂学会-青年委员。

    江苏省毒理学会放射毒理专业委员会-委员(秘书)。

 

代表性论著:

 

    1. Hailong Pei#, Wentao Hu# , Ziyang Guo#, Huaiyuan Chen, Ji Ma, Weidong Mao, Bingyan Li, Aiqing Wang, Jianmei Wan, Jian Zhang, Jing Nie, Guangming Zhou*, and Tom K. Hei*. Long non-coding RNA CRYBG3 blocks cytokinesis by directly binding G-actin. Cancer Research. 2018; 15;78(16):4563-4572.

    2. Ziyang Guo, Yingchu Dai, Wentao Hu, Yongsheng Zhang, Zhifei Cao, Weiwei Pei, Ningang Liu, Jing Nie, Anqing Wu, Weidong Mao, Lei Chang, Bingyan Li, Hailong Pei*, Tom K Hei*, Guangming Zhou*. The long noncoding RNA CRYBG3 induces aneuploidy by interfering with spindle assembly checkpoint via direct binding with Bub3. Oncogene. 2021; 40(10):1821-1835. (Co-Correspondence author)

    3. Anqing Wu, Jiaxin Tang, Ziyang Guo, Yingchu Dai, Jing Nie, Wentao Hu, Ningang Liu; Caiyong Ye, Shihong Li, Hailong Pei*, Guangming Zhou*; Long Non-Coding RNA CRYBG3 Promotes Lung Cancer Metastasis via Activating the  EF1A1/MDM2/MTBP Axis, International Journal Of Molecular Sciences, 2021, 22(6): 3211. (Co-Correspondence author)

    4. Weidong Mao#, Ziyang Guo#, Yingchu Dai1#, Jing Nie, Bingyan Li, Hailong Pei*, Guangming Zhou*. LNC CRYBG3 inhibits tumor growth by inducing M phase arrest. Journal of Cancer. 2019; 10(12): 2764-2770. (Co-Correspondence author)

    5. Hailong Pei, Ziyang Guo, Ziyang Wang, Yingchu Dai, Lijun Zheng, Lin Zhu, Jian Zhang, Wentao Hu, Jing Nie, Weidong Mao, Xianghong Jia, Bingyan Li, Tom K. Hei & Guangming Zhou. RAC2 promotes abnormal proliferation of quiescent cells by enhanced JUNB expression via the MAL-SRF pathway. Cell Cycle. 2018 17( 9), 1115–1123.

    6. Huaiyuan Chen ,* Hailong Pei ,* Wentao Hu ,* Ji Ma, Jian Zhang, Weidong Mao, Jing Nie, Chao Xu, Bingyan Li, Tom K. Hei, Chang Wang, and Guangming Zhou. Long non-coding RNA CRYBG3 regulates glycolysis of lung cancer cells by interacting with lactate dehydrogenase A. Journal of Cancer. 2018; 9(14): 2580–2588. (Co-first author)

    7. Wentao Hu#, Hailong Pei#, Fang Sun, Pengfei Li, Jing Nie, Bingyan Li, Tom K. Hei and Guangming Zhou. Epithelialmesenchymal transition in non-targeted lung tissues of Kunming mice exposed to X-rays is suppressed by celecoxib. Journal of Radiation Research, 2018, pp. 1–5. (Co-first author)

    8. Hailong Pei, Jian Zhang, Jing Nie, Nan Ding, Wentao Hu, Junrui Hua, Ryoichi Hirayama, Yoshiya Furusawa, Cuihua Liu, Bingyan Li, Tom K. Hei, Guangming Zhou. RAC2-P38 MAPK-dependent NADPH oxidase activity is associated with the resistance of quiescent cells to ionizing radiation. Cell Cycle. 2017, 16(1):113-122.

    9. Hailong Pei, Weiqiang Chen, Wentao Hu, Mingyue Zhu, Tingting Liu, Jufang Wang, Guangming Zhou. GANRA-5 Protects both Cultured Cells and Mice from Various Radiation Types by Functioning as a Free Radical Scavenger. Free Radical Research. 2014, 48(06): 670 - 678.

    10. Wentao HU#, Hailong PEI#, He LI, Nan DING, Jinpeng HE, JufangWANG, Yoshiya FURUSAWA, Ryoichi HIRAYAMA, Yoshitaka MATSUMOTO, Cuihua LIU, Yinghui LI, Tetsuya KAWATA and Guangming ZHOU. Effects of shielding on the induction of 53BP1 foci and micronuclei after Fe ion exposures. Journal of Radiation Research. 2013, 55(1): 10-16. (Co-first author)

 

招生信息:

  

招收放射医学、特种医学、分子生物学、细胞生物学、免疫学、病理学及相关专业背景的研究生。