CHEN, Qian

CHEN, Qian

Professor

Academic History:

B.S., Soochow University, College of Chemistry, Chemical Engineering and Materials Science, 2013

Ph.D., Soochow University, Institute of Functional Nano & Soft Materials (FUNSOM), 2017

Post-Doc., University of North Carolina at Chapel Hill, Dept. of Joint Department of Biomedical Engineering, 2017-2018

Post-Doc., University of California, Los Angeles (UCLA), Dept. of Bioengineering, 2018-2019

Professor, Soochow University, FUNSOM, 2019-

Email: chenqian@suda.edu.cn

Research Interests:

Polymer and biomaterials

Bioresponsive drug delivery system

Cancer immunotherapy

Tissue engineering

Research Experience and Accomplishments:

Our research focuses on leveraging biomaterials and biomedical engineering strategy for applications in multimodal biomedical imaging, drug delivery, cancer immunotherapy, and tissue engineering. Dr. Chen has authored over 40 peer-reviewed papers in Nat Nanotechnol, Nat. Commun, Proc Natl Acad Sci USA, Adv Mater, ACS Nano, which have received a total citation of > 3000 times and given her an H-index at 25.

Selected Publications：

1. Qian Chen, Chao Wang, Xudong Zhang, Quanyin Hu, Hongjun Li, Guojun Chen, Jinqiang Wang, Di Wen, Yuqi Zhang, Guang Yang, Jun Wang, Gianpietro Dotti, and Zhen Gu*. “In Situ Sprayed Bioresponsive Immunotherapeutic Gel for Post-Cancer Surgical Treatment”, Nat. Nanotechnol., 14, 89–97 (2019).

2. Qian Chen, Jiawen Chen, Zhijuan Yang, Jun Xu, Ligeng Xu, Chao Liang, Xiao Han, Zhuang Liu*, “Nanoparticle-enhanced radiotherapy to trigger robust cancer immunotherapy”, Adv. Mater., (2019).

3. Qian Chen, Chao Liang, Xiaoqi Sun, Jiawen Chen, Zhijuan Yang, He Zhao, Liangzhu Feng, and Zhuang Liu*. “H₂O₂-responsive Liposomal Nanoprobe for Photoacoustic Inflammation Imaging and Tumor Theranostics via In Vivo Chromogenic Assay”, Proc. Natl. Acad. Sci. U.S.A., 114(21), 5343-5348 (2017).

4. Qian Chen†, Ligeng Xu†, ChaoLiang, Chao Wang, Rui Peng, and Zhuang Liu*. “Photothermal Therapy with Immune-adjuvant Nanoparticles Together with Checkpoint Blockade for Effective Cancer Immunotherapy”, Nat. Commun., 7, 13193 (2016).

5. Qian Chen, Liangzhu Feng, Jingjing Liu, Wenwen Zhu, Ziliang Dong, Yifan Wu, Zhuang Liu* “Intelligent Albumin–MnO₂ Nanoparticles as pH-/H2O2-Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy”, Adv. Mater., 28, 7129-7136 (2016).

6. Qian Chen, Zhuang Liu* “Albumin carriers for cancer theranostics: a conventional platform with new promises”, Adv. Mater., 28, 10557-10566 (2016).

7. Qian Chen, Xiaodong Liu, Jiawen Chen, Jianfeng Zeng*, Zhenping Cheng, Zhuang Liu* “A Self-assembled Albumin-based Nanoprobe for in vivo Ratiometric Photoacoustic pH Imaging”, Adv. Mater., 27, 6820–6827 (2015).

8. Qian Chen, Xin Wang, Chao Wang, Liangzhu Feng, Yonggang Li, Zhuang Liu* “Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy”, ACS Nano, 9, 5223-5233 (2015).

9. Qian Chen, Chao Liang, Chao Wang, Zhuang Liu*, “An Imagable and Photothermal “Abraxane-Like” Nanodrug for Combination Cancer Therapy to Treat Subcutaneous and Metastatic Breast Tumors”, Adv. Mater., 27, 903-910 (2015).

Edited by Juan Yang