Associate Prof. Binbin Chu
Education and Professional Experiences
2023.09–Present: Associate Professor, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, China. (PI: Prof. Yao He)
2020.09–2023.08: Postdoctoral fellow, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, China. (Advisor: Prof. Yao He)
2017.09–2020.06: Ph.D. in Chemistry, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, China. (Advisor: Prof. Yao He)
2014.09–2017.06: Master's degree in Biology, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, China. (Advisor: Prof. Yao He)
2010.09–2014.06: Bachelor's degree, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, China. (Advisor: Prof. Yao He)
Research Interests
Nanoprobes
Bioimaging and Sensor
Ocular diseases
Awards and Funding
2023 Soochow University’s Outstanding Young Scholar
2021 China Postdoctoral Science Foundation project
2022 National Natural Science Foundation of China project
Publications
1. Ding, J. L.; # Lu, J.; # Zhang, Q.; Xu, Y.; Song, B.; Wu, Y.; Shi, H.; Chu, B. B.; * Wang, H.; * He, Y. * Camouflage nanoparticles enable in situ bioluminescence-driven optogenetic therapy of retinoblastoma. ACS Nano 2023,17, 7750-7764.
2. Chu, B.; # Chen, Z.; # Shi, H. L.; Wu, X.; Wang, H.; Dong, F.; * He, Y. * Fluorescence, ultrasonic and photoacoustic imaging for analysis and diagnosis of diseases. Chem. Commun. 2023, 59, 2399-2412.
3. Lu, J.; # Ding J.; #Chu, B.; # Ji, C.; Zhang, Q.; Xu, Y.; Song, B.; * Wang, H.; * He, Y. * Inactive Trojan bacteria as safe drug delivery vehicles crossing blood brain barrier. Nano Lett. 2023, 10, 4326-4333. (# Co-first author)
4. Liu, M.; #Chu, B.; # Sun, R.; Ding, J.; Ye, H.; Yang, Y.; Wu, Y.; Shi, H.; Song, B.; Hong, J.; * Wang, H. Y.; * He, Y. * Antisense oligonucleotides selectively enter human-derived antibiotic-resistant bacteria through bacterial-specific ATP-binding cassette sugar transporter. Adv. Mater. 2023, 35, 2300477. (# Co-first author)
5. Chu, B.; # Yang, Y.; # Tang, J.; Song, B.; He, Y.; * Wang, H. * Trojan nanobacteria system for photothermal programmable destruction of deep tumor tissues. Angew. Chem. Int. Ed. 2022, 61, e202208422.
6. Chu, B.; # Qin, X.; # Zhu, Q. Q.; Wang, H.; Wen, Z.; * Sun, X.; * He, Y.; * Lee, S. T. Triboelectric current stimulation alleviates in vitro cell migration and in vivo tumor metastasis. Nano Energy 2022, 100, 107471.
7. Chu B., He Y. * Silicon-based nanoprobes for imaging detection and therapy of ocular diseases. Chem. J. Chinese Universities, 2022, 43, 20220546.
8. Yang, Y.; #Chu, B.; # Cheng, J. Y.; Tang, J.; Song, B.; Wang, H. Y.; * He, Y. * Bacteria eat nanoprobes for aggregation-enhanced imaging and killing diverse microorganisms. Nat. Commun. 2022, 13, 1255. (# Co-first author)
9. Chu, B.; # Wu, S.; # Yang, Y.; Song, B.; Wang, H.; * He, Y. * Multifunctional flavonoid-silica nanohydrogel enables simultaneous inhibition of tumor recurrence and bacterial infection in post-surgical treatment. Small 2022, 18, 2104578.
10. Chu, B.; # Wang, A.; # Cheng, L.; Chen, R.; Shi, H.; Song, B.; Dong, F.; Wang, H.; * He, Y. * Ex vivo and in vivo fluorescence detection and imaging of adenosine triphosphate. J. Nanobiotechnol. 2021, 19, 187.
11. Chu, B.; Wang, H.; * He, Y. * Fluorescent silicon-based nanomaterials imaging technology in diseases. Chem. Res. Chinese Universities 2021, 37, 880-888.
12. Tang, J.; # Chu, B.; # Wang, J.; Song, B.; Su, Y.; Wang, H.; * He, Y. * Multifunctional nanoagents for ultrasensitive imaging and photoactive killing of Gram-negative and Gram-positive bacteria. Nat. Commun. 2019, 10, 4057. (# Co-first author)
13. Chu, B.; # Wu, S.; # Ji, X.; Chen, R.; Song, B.; Tang, J.; Wang, H.; Su, Y.; He, Y. * Controllable silicon nanostructures featuring stable fluorescence and intrinsic in vitro and in vivo anti-cancer activity. J. Mater. Chem. B 2019, 7, 6247-6256.
14. Chu, B.; # Peng, F.; # Wang, H.; Su, Y.; He, Y. * Synergistic effects between silicon nanowires and doxorubicin at non-toxic doses lead to high-efficacy destruction of cancer cells. J. Mater. Chem. B 2018, 6, 7378-7382.
15. Chu, B.; # Song, B.; # Ji, X. Y.; Su, Y. Y.; Wang, H.; * He, Y. *Fluorescent silicon nanorods-based ratiometric sensors for long-term and real-time measurements of intracellular pH in live cells. Anal. Chem. 2017, 89, 12152-12159.
16. Chu, B.; # Wang, H. Y.; # Song, B.; Peng, F.; Su, Y. Y.; He, Y. * Fluorescent and photostable silicon nanoparticles sensors for real-time and long-term intracellular pH measurement in live cells. Anal. Chem. 2016, 88, 9235-9242.
Edited by Juam Yang