孙欢利博士，18新利体育 研究员。2008和2013年18新利体育 获学士和博士学位，2011年1-2月在荷兰帝斯曼公司培训学习。2013-2015年澳大利亚墨尔本大学博士后，2015年受聘为18新利体育 副教授，2023年晋升为研究员。担任Frontiers in Biomaterials Science副主编，2015年-2022年先后担任Biomacromolecules和J. Controlled Release的副主编助理。在国际主流期刊如Advanced Materials，Nano Today，Advanced Drug Delivery Reviews，Biomaterials，J. Controlled Release等上发表论文50余篇，被引用2900余次，单篇最高被引423次。以第一发明人申请中国和国际发明专利9项，授权4项。主持国家自然科学基金面上项目2项和江苏省自然18新利备用网站 重大项目1项，已顺利完成国家自然科学基金青年基金和江苏省自然科学基金青年基金各1项，作为研究骨干参与国家重点研发计划等多项国家级项目。获江苏高校“青蓝工程”优秀青年骨干教师培养对象和苏州市高等院校、科研院所高层次人才资助计划。

主要研究方向为抗体工程化囊泡纳米药物及多药纳米药物用于癌症的靶向/协同治疗。

‍‍代表性著作 

[1] S. Yue, J. An, Y. Zhang, J. Li, C. Zhao, J. Liu, L. Liang, H. Sun*, Y. Xu*, Z. Zhong*, Exogenous antigen upregulation empowers antibody targeted nanochemotherapy of leukemia. Advanced Materials2023, 35, 2209984.

[2] J. Du, S. Yue, C. Li, J. Li, S. Zhao, Y. Dong, Y. Zhang, R. Cheng, H. Sun*, Z. Zhong*, Exogenous CD38 upregulation enables high-efficacy dually cascade targeted molecular therapy of leukemia. Nano Today2023, 50, 101872.

[3] J. Liu, L. Zhang, D. Zhao, S. Yue, H. Sun*, C. Ni, Z. Zhong*, Polymersome-stabilized doxorubicin-lipiodol emulsions for high-efficacy chemoembolization therapy. Journal of Controlled Release2022, 350, 122-131.

[4] Y. Zhang, J. An, Y. Shao, N. Yu, S. Yue, H. Sun*, J. Zhang, W. Gu, Y. Xia, J. Zhang, Y. Xu*, Z. Zhong*, CD38-directed vincristine nanotherapy for acute lymphoblastic leukemia. Biomacromolecules2022, 23, 377-387.

[5] S. Yue, Y. Zhang, Y. Wei, R. Haag, H. Sun*, Z. Zhong*, Cetuximab–polymersome–mertansine nanodrug for potent and targeted therapy of EGFR-positive cancers. Biomacromolecules2022, 23, 100-111.

[6] N. Yu, Y. Zhang, J. Li, W. Gu, S. Yue, B. Li, F. Meng, H. Sun*, R. Haag, J. Yuan, Z. Zhong*, Daratumumab immunopolymersome-enabled safe and CD38-targeted chemotherapy and depletion of multiple myeloma. Advanced Materials2021, 33, 2007787.

[7] Y. Zhang, S. Yue, R. Haag, H. Sun*, Z. Zhong*, An intelligent cell-selective polymersome-DM1 nanotoxin toward triple negative breast cancer. Journal of Controlled Release2021, 340, 331-341.

[8] H. Sun, Z. Zhong*, 100th anniversary of macromolecular science viewpoint: Biological stimuli-sensitive polymer prodrugs and nanoparticles for tumor-specific drug delivery. ACS Macro Letter2020, 9, 1292-1302.

[9] H. Sun, Z. Zhong*, J. Feijen*, The fifth symposium on innovative polymers for controlled delivery (sipcd 2018), september 14-17, 2018, suzhou, china. Journal of Controlled Release2019, 307, 410-412.

[10] Y. Yan, Y. Dong, S. Yue, X. Qiu, H. Sun*, Z. Zhong*, Dually active targeting nanomedicines based on a direct conjugate of two purely natural ligands for potent chemotherapy of ovarian tumors. ACS Applied Materials & Interfaces2019, 11, 46548-46557.

[11] P. Yao, Y. Zhang, H. Meng, H. Sun*, Z. Zhong*, Smart polymersomes dually functionalized with cRGD and fusogenic gala peptides enable specific and high-efficiency cytosolic delivery of apoptotic proteins. Biomacromolecules2019, 20, 184-191.

[12] L. Ding, W. Gu, Y. Zhang, S. Yue, H. Sun*, J.J.L.M. Cornelissen, Z. Zhong*, HER2-specific reduction-sensitive immunopolymersomes with high loading of epirubicin for targeted treatment of ovarian tumor. Biomacromolecules2019, 20, 3855-3863.

[13] H. Sun, X. Gu, Q. Zhang, H. Xu, Z. Zhong*, C. Deng*, Cancer nanomedicines based on synthetic polypeptides. Biomacromolecules2019, 20, 4299-4311.

[14] H. Sun, Z. Zhong*, Biomacromolecules for emerging biological and medical science and technology. Biomacromolecules2019, 20, 4241-4242.

[15] H. Sun, Y. Zhang, Z. Zhong*, Reduction-sensitive polymeric nanomedicines: An emerging multifunctional platform for targeted cancer therapy. Advanced Drug Delivery Reviews2018, 132, 16-32.

[16] H. Sun, Y. Dong, F. Jan*, Z. Zhong*, Peptide-decorated polymeric nanomedicines for precision cancer therapy. Journal of Controlled Release2018, 290, 11-27.

[17] H. Sun, H.-A. Klok*, Z. Zhong*, Polymers from nature and for nature. Biomacromolecules2018, 19, 1697-1700.

[18] Y. Zhang, K. Wu, H. Sun*, J. Zhang, J. Yuan, Z. Zhong*, Hyaluronic acid-shelled disulfide-cross-linked nanopolymersomes for ultrahigh-efficiency reactive encapsulation and CD44-targeted delivery of mertansine toxin. ACS Applied Materials & Interfaces2018, 10, 1597-1604.